According to Grand View Research, the global oral beauty market will reach US$3.5 billion in 2021, and is expected to grow at an average annual growth rate of 9.2% by 2028, with the market size exceeding US$7 billion. Rapid growth of oral beauty in the Asia-Pacific region.
01 The era of precision peptides has arrived
From "concept melee" to "precision collagen tripeptide"
The 2024 "China Functional Food Development Blue Book" shows that the oral collagen market size has exceeded 30 billion yuan, but the industry is in chaos: 72% of products do not label the content of active ingredients, and 53% of companies do not have core patented technologies. When most players are still selling the concepts of "collagen" and "small molecule peptides", PEPDOO uses the posture of precision peptide making to reshape the standard with the barrier of OKPEP precision peptide making. The research and application of its specially developed BUTILIFE® fish collagen tripeptide with a smaller molecular weight and easier absorption may become a research hotspot in the industry. PEPDOO is a world-leading smart enterprise that masters the core technology of precision peptide production (OKPEP® precision peptide production core technology). It has been deeply engaged in the field of bioactive peptides for 15 years and has participated in the formulation of many industry standards. It has internationally advanced peptide production technology, focuses on technological innovation and product research and development, and realizes the efficient preparation of specific functional peptides. It is committed to promoting the development of the active peptide industry.

02 BUTILIFE® Fish Collagen Tripeptide
Three-dimensional efficacy evidence
Use cellular-level scientific language to accurately convince the world
BUTILIFE® Fish Collagen Tripeptide has three major efficacy certificates issued by a third-party professional organization, [human + animal + cell] triple oral beauty guarantee, 28-day real-person test, dermal collagen increased by 52.26%!
[Human] Oral beauty efficacy certificate:
·Dermis density value increased by 52.26%
·The F4 value of the skin firmness at the corner of the eye decreased by 20.00%
·The area of crow's feet at the corner of the eye decreased by 12.40%
·The number of eye wrinkles decreased by 16.68%
·The R2 value of the skin elasticity at the corner of the eye increased by 10.17%
·The water content of the skin stratum corneum increased by 15.77%
·The ITA° value of skin color increased by 7.54%
·The glossiness of the skin increased 18.13%
·The percentage of pigmentation area decreased by 8.26%[4]
[Animal] Anti-wrinkle efficacy:
In order to verify the function of the patented
BUTILIFE® fish collagen tripeptide, PEPDOO successfully verified the patented BUTILIFE® fish collagen tripeptide by comparing the changes in the zebrafish tail fin area under different control groups and different collagen tripeptide concentrations through a third-party testing agency. The results showed that the patented
BUTILIFE® fish collagen tripeptide can significantly inhibit the shrinkage of the zebrafish tail fin area in the experiment, proving that
BUTILIFE® fish collagen tripeptide has anti-wrinkle and skin elasticity-enhancing effects.

[Cell] Collagen regeneration special certificate:
To further verify the function of the patented BUTILIFE® fish collagen tripeptide, PEPDOO has verified the effect of the patented BUTILIFE® fish collagen tripeptide on cell collagen-l α1 at different concentrations through experiments by a third-party testing agency. The third-party professional agency concluded through experiments: "Under the conditions of this experiment, the concentration of collagen-l α1 in the positive control group (PC) was significantly increased compared with the negative control group (NC) (P<0.001), indicating that the positive response is normal: the sample group at a concentration of 6mg/mL, the concentration of collagen-1 α1 was significantly increased compared with the negative control group (NC) (P=0.05). The sample at a concentration of 6mg/ml can promote the expression of collagen-l α1 and has a firming effect."
From "eating collagen" to "growing collagen": precise crossing at the nano level
The molecular weight of traditional collagen peptides is mostly 1000-3000Da, and needs to be enzymatically hydrolyzed into amino acid fragments by the intestines. However, PEPDOO BUTILIFE® fish collagen tripeptide breaks through the "absorption ceiling" with nano-scale small molecules (like 1/3000 of a hair) - it quickly reaches the dermis, and the absorption rate is about 5 times that of ordinary peptides.
03 Breakthrough in precision peptide technology
From "rough processing" to "nano-level precision peptide"
OKPEP precision peptide technology: "industrial mother machine" for molecular-level tailoring
OKPEP precision peptide technology: Combining AI intelligent machine learning and live cell functional target screening dual-engine technology, accurately identify the characteristic amino acid sequence functional peptides with stable structure-activity relationship, and use specific proteases to perform targeted and precise cutting of substrate proteins to obtain high-quality characteristic target functional peptides.
AI algorithm driven: screen out precise and highly specific proteases through virtual enzymatic hydrolysis system to achieve precise cutting of collagen peptide sequences.
Precision peptide feature map library: "gene ID card" of collagen tripeptide
Integrating a large amount of precise active peptide feature information, using advanced analysis technology and AI algorithms, accurately analyzing and recording key features such as active peptide amino acid sequence, spatial structure, and biological active sites; scientific researchers and production personnel can quickly and accurately identify and analyze target active peptides, just like having a "fingerprint identification manual" in the field of precision peptide. It not only helps to accelerate the screening and development of active peptides, but also provides an important basis for quality control and standardized production of functional peptide products.
04 PEPDOO OKPEP
Continue to lead the precision peptide market
Right to speak on standards
As the drafting unit of peptide standards such as "Collagen Tripeptide", "Marine Animal Peptide" and "Plant Peptide", PEPDOO takes the lead in formulating the industry's active peptide detection methods as a standard setter;
Relying on the core technology of precision peptide preparation, PEPDOO has made precise efforts on the application side to meet diversified needs in all aspects and become the leading brand of China's active peptide industry.
Precise empowerment pool
The group has more than 150+ patents, 40,000+㎡ production base, 4,000+ product solutions, and an annual output of precision active peptides of more than 6,000 tons, etc.
Domestic leading and internationally advanced peptide preparation technology
As a leading enterprise in the emerging marine industry, PEPDOO has invested a lot of scientific research resources to focus on the completion of the technical research and application results of "Marine oligopeptides developed based on new microbial combined characteristic bioenzyme method", which has been evaluated as reaching the international advanced level overall.

In the oral beauty market, collagen products continue to lead the market with an annual market share of 78%[9]. Consumers’ pursuit of “effectiveness” has forced the industry to innovate. PEPDOO has redefined the anti-aging standard with BUTILIFE® fish collagen tripeptide - achieved through OKPEP precision peptide production technology, so that every drop of precision peptide raw materials can stand the test of the market!