Histori ea Tšebeliso ea Ginseng Bophelong le Bongaka

Selelekela

Ginseng e 'nile ea hlomphuoa ka nako e telele e le e' ngoe ea litlama tse matla ka ho fetisisa le tsa setso sa meriana ea setso. Ka nalane ea eona e ruileng ea nalane le bohlokoa bo ntseng bo hola ho mahlale a sejoale-joale a bophelo bo botle, ginseng e bile teng ho tloha motsong o makatsang ho ea setsing sa matla sa bioactive. Kajeno, tsoelopele eali-peptide tsa ginsenge emela moeli o mocha oa phepo e nepahetseng, e matlafatsang melemo ea litlama ka mekhoa e tsoetseng pele ea ho ntša [1].

Tšimoloho le Metso ea Setso sa Ginseng

Lebitso"Panax"e tsoa lentsoeng la Segerike le bolelang "pholiso eohle," le bontšang maikutlo a boholo-holo a ginseng e le pheko ea bokahohle. Tšebeliso ea pele e tlalehiloeng eaPanax ginsenge qalile ka lilemo tse fetang 2,000 Chaena, moo e neng e nkoa e le ea bohlokoa bakeng sa bokhoni ba eona ba ho tsosolosa matla le ho phekola maloetse a sa tšoaneng [2]. Kwa Korea, ginseng ya naga e ne e tsewa e le letlotlo la setšhaba, le gantsi le neng le beetswe ba segosi. Ho sa le joalo, lichaba tsa Matsoalloa a Amerika li ne li sebelisoaPanax quinquefolius, kapa ginseng ea Amerika, bakeng sa liphello tsa eona tse khutsitseng le tse matlafatsang.

Ho theosa le makholo a lilemo, ginseng e ile ea kenella ka ho teba litloaelong tsa setso le litsamaiso tsa bongaka, tse tšoantšetsang bophelo bo bolelele, matla le ho leka-lekana. Le hoja ka tloaelo e sebelisoa e le metso kapa li-decoctions, lipatlisiso tsa morao-rao li fumane metsoako e khethehileng e sebetsang, e kang ginsenosides le peptide, e ikarabellang bakeng sa liphello tsa eona tse ngata tsa phekolo [3].

Ginseng ho Mekhoa ea Setso ea Bongaka

Ka Traditional Chinese Medicine (TCM), ginseng e hlalosoa e le setlama se hloahloa se sebelisetsoang ho matlafatsa Qi, ho matlafatsa spleen, le ho tšehetsa tšebetso ea matšoafo. Lihlahisoa tsa litlama joalo kaRen Shen TangleGui Pi Tangtotobatsa karolo ea eona ea motheo ea ho khutlisetsa matla le ho khothaletsa kutloano ea ka hare.

Korea le Japane, ginseng le eona ke motheo oa litloaelo tsa bongaka. Ginseng e khubelu ea Korea, e sebetsoang ka mouoane le ho omisoa, e ratoa haholo-holo ka lebaka la matla a eona a matlafalitsoeng. Meriana ea Kampo ea Majapane, ginseng e ntse e tsoela pele ho ba motsoako oa bohlokoa liforomong tse etselitsoeng ho ntlafatsa botsitso le ts'ebetso ea metabolic.

Lisebelisoa tsena tsa setso li ralile motheo oa mekhoa ea sejoale-joale e kang li-peptide tsa ginseng, tse khethollang le ho tsepamisa maikutlo likaroloana tsa limolek'hule tsa bioactive bakeng sa liphetho tse lebisitsoeng tsa bophelo bo botle [4].

Phatlalatso ea Saense le Likarolo tse sebetsang

Ginseng e na le letoto le rarahaneng la metsoako e sebetsang, ho kenyelletsa ginsenosides, polysaccharides, le oli ea bohlokoa. Lilemong tse mashome tsa morao tjena, bo-rasaense ba sibolotse le ho ithuta li-peptide tsa ginseng-liprotheine tse khutšoanyane tse fumanoang ka enzymatic hydrolysis ea metso ea ginseng.

Li-peptide tsa Ginseng li fapana le li-extracts tsa setso ka bioavailability ea tsona e ntlafalitsoeng le botsitso. E hlahisoa ka lits'ebetso tsa enzymatic, li-peptide tsena li boloka boleng ba thepa ea pharmacological ea ginseng ha e ntse e fana ka litlamorao tse lebisitsoeng tsa 'mele [5].

Boithuto bo bonts'itse hore li-peptide tsa ginseng li bonts'a mesebetsi ea antioxidant, anti-inflammatory, neuroprotective le taolo ea 'mele ea ho itšireletsa mafung. Lintho tsena li li etsa hore li tšoanelehe bakeng sa mefuta e mengata ea likopo, ho tloha ho lijo tse sebetsang ho ea ho phepo ea kliniki [6].

Lisebelisoa tsa Kajeno tsa Bophelo bo Botle le Phepo

Ginseng e fumane bophelo bo bocha lijong tsa sejoale-joale tsa phepo e nepahetseng le lino tse sebetsang tse reretsoeng ho matlafatsa ts'ebetso ea kelello le matla. Ho eketsoa ha li-peptide tsa ginseng lihlahisoa tsena ho lebisitse ho ts'ebetsong e ntlafetseng, haholo-holo ho loants'eng mokhathala le ho khothalletsa ho hlaka ha kelello [7].

Thepa ea bona ea adaptogenic e boetse e etsa hore li-peptide tsa ginseng li atlehe ho ts'ehetsa botsitso ba khatello ea maikutlo le botsitso ba 'mele. Lithuto tsa mahlale li bonts'itse bokhoni ba bona ba ho fetola maemo a cortisol, ho eketsa ts'ebetso ea lisele tsa 'molai oa tlhaho (NK), le ho fokotsa ho ruruha [8].

Ho feta moo, li-peptide tsa ginseng li hlahile e le li-anti-botsofali tse tšepisang. Ka ho sireletsa ts'ebetso ea mitochondrial le ho khothaletsa collagen synthesis, ba ts'ehetsa bophelo bo botle ba letlalo, ho leka-lekana ha metabolism, le matla ka kakaretso [9].

Ntlafatso ea Lefatše ea Liindasteri

China, Korea le United States ke tsona tse etellang pele lihlahisoa tsa ginseng, tse nang le lisebelisoa tse inehetseng bakeng sa temo le ts'ebetso e tsoetseng pele. Tlhahiso ea li-peptide tsa ginseng e hloka lisebelisoa tse khethehileng tsa theknoloji ea biotechnology ho netefatsa ts'ebetso ea enzymatic le poloko ea bioactive.

Mmaraka oa lihlahisoa tse thehiloeng ho ginseng peptide o ntse o hola ka potlako. Li-peptide tsena joale li kenyellelitsoe ho li-supplement tse phofshoana, lithunya tse seng li loketse ho nooa, le li-sachets tse lebisitseng bareki ba tsotellang bophelo bo botle. Lefapheng la B2B, metsoako ea ginseng ea peptide e batloang haholo bakeng sa metsoako e sebetsang [10].

Mekhatlo ea taolo ea lefats'e joalo ka EFSA le CFDA e ntse e lemoha butle-butle li-peptide tse nkiloeng ho ginseng, ha boqapi bo ntse bo tsoela pele ka mekhoa e nang le tokelo ea molao le liteko tsa bongaka tse reretsoeng ho paka melemo ea bona ea ts'ebetso [11].

Ginseng Peptides: Moeli oa Kajeno

Li-peptide tsa Ginseng li emela tsoelo-pele e tsoetseng pele ho tsa biotechnology ea litlama. Li-peptide tsena tse boima bo tlase ba limolek'hule li nkiloe ho liprotheine tsa motso oa ginseng ka enzymatic hydrolysis, li etsa hore ho be bonolo hore 'mele o monye le ho o sebelisa.

Mekhoa ea bona ea tlhaho e kenyelletsa ho feto-fetoha ha khatello ea oxidative, ntlafatso ea tokiso ea lisele, le taolo ea 'mele ea ho itšireletsa mafung. Ha li bapisoa le li-extracts tse tala, li-peptide tsa ginseng li bonts'a ho qhibiliha ho holimo, ho monya, le ketso e lebisitsoeng, e li beha e le metsoako ea pele molokong o latelang oa limatlafatsi [12].

Mathata le Likhohlano

Leha ho na le litšoaneleho tse ngata tse ts'episang tsa ginseng le li-peptide tsa eona, indasteri e tobane le liphephetso tse joalo ka bohlola, maemo a sa tsitsang, le khaello ea netefatso e tšoanang ea bongaka. Ha se lihlahisoa tsohle tse 'marakeng tse nang le maemo a netefalitsoeng ke mahlale a metsoako e sebetsang, mme tlhokomeliso ea bareki e ntse e lekanyelitsoe [13].

Boiteko bo ntse bo tsoela pele ho tiisa boleng ba peptide ea ginseng, ho ntlafatsa mekhoa ea liteko tsa tleliniki, le ho theha meralo ea taolo ea lefats'e e ka netefatsang ts'ebetso le polokeho.

Maikutlo a Bokamoso

Bokamoso ba ginseng bo holim'a phepo e nepahetseng, moo li-peptide tsa ginseng li tla bapala karolo ea bohlokoa litharollong tsa bophelo bo botle. Litlhahiso tse kang li-nanocarriers, litlhare tsa tokollo e tšoarellang, le tšebelisano le li-bioactive tse ling li kanna tsa ntlafatsa phihlello ea kalafo ea li-peptide tsa ginseng.

Ho feta moo, ha bareki ba ntse ba batla litharollo tsa tlhaho, tse tšehelitsoeng ke bopaki bakeng sa matla, botsofali, ho itšireletsa mafung, le ts'ebetso ea kelello, li-peptide tsa ginseng e kanna ea ba karolo ea mantlha ea maano a sejoale-joale a bophelo bo botle [14].

Qetello

Ho tloha karolong ea eona e halalelang meriana ea khale ho ea boemong ba eona bo hlahang e le peptide e sebetsang, ginseng e ntse e tsoela pele ho susumetsa le ho fetoha. Ho phahama ha li-peptide tsa ginseng ho tšoaea phetoho ea phetoho, e nolofalletsang melemo e tebileng ea bophelo bo botle ka mahlale a sejoale-joale ntle le ho lahleheloa ke metso ea setso.

Litšupiso

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• [2] Qi LW, Wang CZ, Yuan CS.Ginsenosides e tsoang ho ginseng ea Amerika: Phapang ea lik'hemik'hale le ea meriana.
• [3] Christensen LP.Ginsenosides chemistry, biosynthesis, tlhahlobo, le litlamorao tse ka bang teng tsa bophelo bo botle.
• [4] Liu CX, Xiao PG.Khatelo-pele ea morao-rao ea lipatlisiso tsa ginseng Chaena.
• [5] Kim DH.Phapang ea lik'hemik'hale ea motso oa ginseng, motso oa quinquifolium, le motso notoginseng.
• [6] Wang J, Li S.Li-peptide tsa bioactive tse tsoang ho ginseng: Sesebelisoa se secha se ka bang teng bakeng sa lijo tse sebetsang.
• [7] Reay JL, Kennedy DO, Scholey AB.Liphello tsa Panax ginseng temohong, maikutlong le mokhathala.
• [8] Lee DC, Yang CL.Liphello tsa immunomodulatory tsa ginseng le ginsenosides tlhahiso ea cytokine.
• [9] Kim HJ, le ba bang.Litlamorao tse khahlanong le botsofali tsa li-peptide tsa ginseng: Tšireletso ea Mitochondrial le nchafatso ea letlalo.
• [10] Lee SM.Mokhoa oa 'maraka le boqapi ba li-peptide tsa ginseng.
• [11] Zhang Y, le ba bang.Tlhahlobo ea bongaka ea li-peptide tsa ginseng ka mokhathala le boits'ireletso.
• [12] Chen L, le ba bang.Tlhahlobo ea sebopeho le bioactivities ea li-peptide tse tsoang ho ginseng.
• [13] Li W, le ba bang.Mathata a ho tiisa litokisetso tsa ginseng.
• [14] Gao Y, le ba bang.Monyetla oa li-peptide tsa ginseng lijong tsa motho ka mong.